Lost every ES key?
An ES with no key left gets its immobilizer reset, and the replacement is enrolled from scratch, with its blade cut to the code tied to your VIN. Pricing is the spare row plus $60: $209 for a 1998 to 2003 ES 300, $229 for an ES 330 and $349 for any ES with a smart key.
The 2019 to 2021 cars deserve an extra search before you call. Under that Lexus bulletin, a key wiped during the reset is locked out of registration on any car afterward, so one that turns up in a jacket a week later is scrap. Bring the registration or title as well, with a license in the same name.